TMR® and reduction of inflammation
Treatment with TMR® can reduce the inflammatory condition of damaged tissue which is common to several different orthopaedic conditions such as chronic arthritis, epicondylitis, tendinitis and wounds resulting from trauma or surgery.
Studies carried out in vitro (1) have shown how TMR® is able to influence mitochondrial function, in particular by reducing the levels of oxidative stress.
In addition, in vivo studies in publication have shown that TMR® is able to promote the persistent reduction of inflammatory infiltrate.
Many orthopaedic diseases are accompanied by acute and / or chronic pain.
Pulsed electromagnetic fields are able to attenuate the painful condition thanks to two different mechanisms.
The first reduces the transmission of nociceptive stimuli, acting in the short term by decreasing the perception of pain in accordance with gate control theory.
The second mechanism is instead able to act long term, counteracting the causes of pain and in particular reducing the inflammatory condition.
At clinical level, TMR® showed evidence of reduced pain perception measured by the Visual Analogue Scale (2).
TMR® in pre- and post-surgery treatment
Therapy with TMR® has proven to be a valuable aid in the resolution and shortening of time of wound closure (2) even in the presence of profound inflammation, thereby contributing to savings in cost of treatment.
TMR® can be of great assistance in reducing pre-operative and post-operative oedema.
(1) Letizia Ferroni, Gloria Bellin, Valeria Emer, Rosario Rizzuto, Maurizio Isola, Chiara Gardin and Barbara Zavan Treatment by Therapeutic Magnetic Resonance (TMR®) increases fibroblastic activity and keratinocyte differentiation in an in vitro model of 3D artificial skin J Tissue Eng Regen Med, Jun 5 2015.
(2) Source: Lorenza Abbruzzese, DPM, Elisabetta Iacopi, MD, Alberto Coppelli, MD, Giovanni Bonino, DPM, Chiara Goretti, MD, e Alberto Piaggesi, MD, Safety and Effectiveness of Therapeutic Magnetic Resonance in the Management of Postsurgical Lesion of the Diabetic Foot, The International Journal of Lower Extremity Wounds, March 2015,14: 4-10.